2011 São Léo Open – Singles

Leonardo Mayer won the first edition of the tournament 7–5, 7–6(7–1) in the final against Nikola Ćirić.

Seeds
• # Rui Machado (semifinals)

• # 🇦🇷 Diego Junqueira (first round)

• # Frederico Gil (first round)

• # 🇦🇷 Leonardo Mayer (champion)

• # 🇧🇷 Ricardo Mello (quarterfinals)

• # 🇪🇸 Rubén Ramírez Hidalgo (quarterfinals)

• # 🇦🇷 Máximo González (second round)

• # 🇺🇸 Wayne Odesnik (quarterfinals)