2013 Challenger Ciudad de Guayaquil – Singles

Leonardo Mayer defended his title over Portuguese Pedro Sousa 6–4, 7–5.

Seeds
• # 🇦🇷 Leonardo Mayer (champion)

• # 🇮🇹 Paolo Lorenzi (first round)

• # 🇦🇷 Diego Sebastián Schwartzman (first round)

• # 🇺🇸 Wayne Odesnik (second round)

• # Paul Capdeville (second round)

• # Gastão Elias (first round)

• # 🇦🇷 Máximo González (second round)

• # 🇩🇴 Víctor Estrella Burgos (quarterfinals)