2017 Milo Open Cali – Singles

Darian King was the defending champion but chose not to defend his title.

Federico Delbonis won the title after defeating Guilherme Clezar 7–6(12–10), 7–5 in the final.

Seeds
• # 🇦🇷 Horacio Zeballos (first round)

• # 🇦🇷 Federico Delbonis (champion)

• # 🇩🇴 Víctor Estrella Burgos (first round)

• # 🇪🇸 Roberto Carballés Baena (quarterfinals)

• # 🇦🇹 Gerald Melzer (semifinals)

• # 🇸🇰 Jozef Kovalík (first round)

• # 🇪🇸 Ricardo Ojeda Lara (second round)

• # 🇸🇰 Andrej Martin (semifinals)