2019 Open Sopra Steria de Lyon – Singles

Félix Auger-Aliassime was the defending champion but chose not to defend his title.

Corentin Moutet won the title after defeating Elias Ymer 6–4, 6–4 in the final.

Seeds
All seeds receive a bye into the second round. • # 🇪🇸 Albert Ramos Viñolas (quarterfinals)

• # 🇪🇸 Pablo Andújar (third round)

• # 🇫🇷 Corentin Moutet (champion)

• # 🇸🇪 Elias Ymer (final)

• # Pedro Sousa (third round)

• # 🇪🇸 Pedro Martínez (second round)

• # 🇮🇹 Gianluca Mager (withdrew)

• # 🇫🇷 Quentin Halys (second round)

• # 🇪🇸 Enrique López Pérez (second round)

• # 🇩🇪 Rudolf Molleker (third round)

• # 🇧🇪 Kimmer Coppejans (quarterfinals)

• # 🇧🇪 Arthur De Greef (second round)

• # 🇫🇷 Maxime Janvier (third round)

• # 🇫🇷 Constant Lestienne (second round)

• # 🇨🇴 Daniel Elahi Galán (second round)

• # Tallon Griekspoor (second round, retired)