2019 Open du Pays d'Aix – Singles

John Millman was the defending champion but chose not to defend his title.

Pablo Cuevas won the title after defeating Quentin Halys 7–5, 3–6, 6–2 in the final.

Seeds
All seeds receive a bye into the second round. • # Pablo Cuevas (champion)

• # 🇨🇿 Jiří Veselý (second round)

• # Lloyd Harris (third round)

• # 🇺🇿 Denis Istomin (second round)

• # 🇧🇷 Thiago Monteiro (third round)

• # 🇩🇪 Yannick Maden (second round)

• # 🇫🇷 Grégoire Barrère (second round)

• # 🇪🇸 Guillermo García López (second round)

• # 🇨🇦 Peter Polansky (second round)

• # 🇮🇹 Stefano Travaglia (third round)

• # 🇫🇷 Antoine Hoang (third round)

• # 🇮🇹 Gianluca Mager (quarterfinals)

• # 🇺🇸 Marcos Giron (second round)

• # 🇩🇪 Rudolf Molleker (third round)

• # 🇮🇹 Simone Bolelli (withdrew)

• # 🇮🇹 Lorenzo Giustino (second round)