2020 Monterrey Challenger – Singles

Alexander Bublik was the defending champion but chose not to defend his title.

Adrian Mannarino won the title after defeating Aleksandar Vukic 6–1, 6–3 in the final.

Seeds
All seeds receive a bye into the second round. • # 🇫🇷 Adrian Mannarino (champion)

• # 🇪🇸 Feliciano López (second round)

• # 🇪🇸 Pablo Andújar (quarterfinals)

• # 🇱🇹 Ričardas Berankis (third round)

• # 🇦🇷 Federico Coria (second round)

• # Jason Jung (quarterfinals)

• # 🇮🇹 Paolo Lorenzi (third round)

• # 🇮🇹 Federico Gaio (second round)

• # 🇮🇹 Lorenzo Giustino (third round)

• # 🇨🇦 Steven Diez (second round)

• # 🇷🇸 Viktor Troicki (second round)

• # 🇨🇦 Brayden Schnur (second round)

• # 🇦🇺 Andrew Harris (third round)

• # 🇨🇦 Peter Polansky (third round)

• # 🇦🇺 Bernard Tomic (third round)

• # 🇺🇸 Ernesto Escobedo (semifinals)