2021–22 Drexel Dragons women's basketball team

The 2021–22 Drexel Dragons women's basketball team represented Drexel University during the 2021–22 NCAA Division I women's basketball season. The Dragons, led by second-year head coach Amy Mallon, played their home games at the Daskalakis Athletic Center in Philadelphia, Pennsylvania as members of the Colonial Athletic Association.

Previous season
The Dragons finished the 2020–21 season 14–9, 8–6 in CAA play to finish tied for third place. They defeated Delaware in the CAA tournament championship, and earned an automatic bid to the 2021 NCAA Division I women's basketball tournament.

Preseason
In a poll of the league coaches, media relations directors, and media members at the CAA's media day, Drexel was picked to finish in first place in the CAA. Hannah Nihill and Keishana Washington were named to the preseason All-CAA first team.

Schedule and results
!colspan=12 style=| Exhibition

!colspan=12 style=| Non-conference regular season

!colspan=12 style=| CAA regular season

!colspan=12 style=| CAA Tournament

!colspan=12 style=| WNIT

Awards

 * Brianne Borcky
 * Steven Sher Academic Award


 * Tessa Brugler
 * CAA All-Conference Second Team
 * City of Basketball Love All–City 6 First Team
 * CAA Player of the Week
 * Rebounding Award (team leader in rebounds)
 * Mo Cronin Spirit & Leadership Award


 * Maura Hendrixson
 * Lil Haas Coaches Award


 * Mariah Leonard
 * Charge Leader Award (team leader in charges drawn)


 * Amy Mallon
 * CAA Coach of the Year


 * Hannah Nihill
 * CAA All-Conference Second Team
 * CAA All-Defensive Team
 * City of Basketball Love All–City 6 Second Team
 * Preseason CAA All-Conference First Team
 * Meghan Creighton Assist Award (team leader in assists)
 * Team Defensive Player of the Year


 * Hetta Saatman
 * Steven Sher Academic Award


 * Jasmine Valentine
 * Liz Berry Most Improved Award (team's most improved player)


 * Keishana Washington
 * CAA All-Conference First Team
 * City of Basketball Love All–City 6 First Team
 * CAA Player of the Week (4)
 * CAA All-Tournament Team
 * CAA Scholar Athlete of the Year
 * Preseason CAA All-Conference First Team
 * Team Most Valuable Player
 * Steven Sher Academic Award