2021–22 Melbourne City FC season

The 2021–22 season was the 12th in the history of Melbourne City Football Club In addition to the domestic league, Melbourne City also competed in the FFA Cup and AFC Champions League. They were managed by Patrick Kisnorbo and captained by Scott Jamieson.

Matches
Notes:

Group stage
The draw for the group stage was held on 17 January 2022. Despite finishing the group stage undefeated with 3 wins and 3 draws; Melbourne City finished in second place due to goal difference, missing out on an automatic spot in the knockout stage of the tournament. They also didn't advance as one of the best runner-ups, due to Jeonbuk Hyundai Motors, Urawa Red Diamonds, and Kitchee performing better than them in their respective groups.

Appearances and goals
''Includes all competitions. Players with no appearances not included in the list.''

Disciplinary record
''Includes all competitions. The list is sorted by squad number when total cards are equal. Players with no cards not included in the list.''

Clean sheets
''Includes all competitions. The list is sorted by squad number when total clean sheets are equal. Numbers in parentheses represent games where both goalkeepers participated and both kept a clean sheet; the number in parentheses is awarded to the goalkeeper who was substituted on, whilst a full clean sheet is awarded to the goalkeeper who was on the field at the start of play. Goalkeepers with no clean sheets not included in the list.''