2021 Little Rock Challenger – Doubles

Matías Franco Descotte and Orlando Luz were the defending champions but chose not to defend their title.

Nicolás Barrientos and Ernesto Escobedo won the title after defeating Christopher Eubanks and Roberto Quiroz 4–6, 6–3, [10–5] in the final.

Seeds
• # 🇺🇸 Robert Galloway / 🇺🇸 Alex Lawson (withdrew)

• # 🇺🇸 Dennis Novikov / Gonçalo Oliveira (semifinals)

• # 🇮🇳 Jeevan Nedunchezhiyan / 🇮🇳 Purav Raja (first round)

• # Ante Pavić /  Ruan Roelofse (first round, retired)