2021 Wimbledon Championships – Girls' singles

Ane Mintegi del Olmo won the title, defeating Nastasja Schunk in the final, 2–6, 6–4, 6–1.

Daria Snigur was the defending champion having won the previous edition in 2019. She participated in the women's singles qualifying competition, losing to Beatriz Haddad Maia in the first round.

Seeds
• 🇦🇩 Victoria Jiménez Kasintseva (semifinals)

• Alex Eala (second round)

• 🇷🇺 Diana Shnaider (first round)

• 🇷🇺 Polina Kudermetova (second round)

• 🇫🇷 Océane Babel (second round)

• 🇧🇾 Kristina Dmitruk (quarterfinals)

• 🇺🇸 Alexandra Yepifanova (second round)

• 🇨🇿 Linda Fruhvirtová (semifinals)

• 🇺🇸 Madison Sieg (first round)

• 🇺🇸 Elvina Kalieva (second round)

•  Priska Madelyn Nugroho (second round)

• 🇵🇪 Dana Guzmán (first round)

• 🇬🇧 Matilda Mutavdzic (third round)

•  Michaela Laki (first round)

• 🇩🇪 Mara Guth (quarterfinals)

• 🇲🇽 Julia García (second round)

Seeds
• # Johanne Svendsen (qualified)

• # 🇷🇺 Ksenia Zaytseva (qualified)

• # 🇨🇦 Annabelle Xu (qualified)

• # 🇨🇿 Nikola Bartůňková (qualified)

• # 🇷🇸 Tijana Sretenović (qualifying competition)

• # 🇫🇷 Lucie Nguyen Tan (first round)

• # 🇯🇵 Mei Hasegawa (qualified)

• # Chelsea Fontenel (qualified)

• # 🇰🇷 Ku Yeon-woo (qualifying competition)

• # 🇷🇺 Elena Pridankina (qualified)

• # 🇷🇺 Anastasiia Gureva (qualifying competition)

• # 🇺🇸 Clervie Ngounoue (qualifying competition)

• # 🇨🇦 Kayla Cross (qualified)

• # 🇫🇷 Anaëlle Leclercq (qualifying competition)

• # 🇰🇿 Tatyana Nikolenko (qualifying competition)

• # 🇷🇴 Fatima Ingrid Amartha Keita (first round)

Qualifiers
• # Johanne Svendsen

• # 🇷🇺 Ksenia Zaytseva

• # 🇨🇦 Annabelle Xu

• # 🇨🇿 Nikola Bartůňková

• # 🇷🇺 Elena Pridankina

• # 🇨🇦 Kayla Cross

• # 🇯🇵 Mei Hasegawa

• # Chelsea Fontenel