2021 Women's Egyptian Squash Open

The Women's 2021 CIB Egyptian Open is the women's edition of the 2021 CIB Egyptian Open, which is a 2021–22 PSA World Tour event. The event will take place in Cairo, Egypt between 10 and 17 September, 2021. The event's main sponsor is the Commercial International Bank of Egypt.

Nouran Gohar beat Nour El Sherbini in an all Egyptian final, being the first time Gohar has won this tournament.

Seeds
• # 🇪🇬 Nour El Sherbini (runner-up)

• # 🇪🇬 Nouran Gohar (champion)

• # 🇪🇬 Camille Serme (semi-finals)

• # 🇳🇿 Amanda Sobhy (semi-finals)

• # 🇪🇬 Sarah-Jane Perry (second round)

• # 🇪🇬 Hania El Hammamy (quarter-finals)

• # 🇪🇬 Salma Hany (quarter-finals)

• # 🇪🇬 Rowan Elaraby (quarter-finals)