2022–23 Cambridge United F.C. season

The 2022–23 season is the 111th season in the existence of Cambridge United Football Club and the club's second consecutive season in League One. In addition to the league, they will also compete in the 2022–23 FA Cup, the 2022–23 EFL Cup and the 2022–23 EFL Trophy.

Pre-season and friendlies
On 30 May, Cambridge United announced their first two pre-season friendlies, against Cardiff City and Norwich City. A third friendly at a neutral ground against Notts County was later confirmed. On June 16, another home friendly was confirmed, against Hull City.

Matches
On 23 June, the league fixtures were announced.

FA Cup
The U's were drawn away to Curzon Ashton in the first round.

EFL Cup
Cambridge were drawn at home to Millwall in the first round and to Southampton in the second round.

EFL Trophy
On 20 June, the initial Group stage draw was made, grouping Cambridge United with Ipswich Town and Northampton Town.