2022 Cali Open – Doubles

This was the first edition of the tournament. The tournament originated as a quick replacement for the 2022 edition of the Quito Challenger, which was moved to Cali due to political unrest in Quito.

Malek Jaziri and Adrián Menéndez Maceiras won the title after defeating Keegan Smith and Evan Zhu 7–5, 6–4 in the final.

Seeds
• # 🇮🇳 Sriram Balaji / 🇮🇳 Jeevan Nedunchezhiyan (semifinals)

• # 🇰🇷 Chung Yun-seong / Michail Pervolarakis (first round)

• # 🇪🇸 Carlos Gómez-Herrera / 🇪🇨 Roberto Quiroz (withdrew)

• # 🇧🇷 Mateus Alves / 🇨🇴 Nicolás Mejía (first round)

• # 🇳🇴 Viktor Durasovic / Gonçalo Oliveira (semifinals)