2022 Engie Open Nantes Atlantique – Singles

Anhelina Kalinina was the defending champion but she chose to compete at the 2022 GB Pro-Series Shrewsbury instead.

Kamilla Rakhimova won the title, defeating Wang Xinyu in the final, 6–4, 6–4.

Seeds
• # 🇩🇪 Tamara Korpatsch (semifinals)

• # 🇫🇷 Océane Dodin (second round)

• # Kamilla Rakhimova (champion)

• # 🇨🇳 Wang Xinyu (final)

• # 🇧🇪 Ysaline Bonaventure (withdrew)

• # Vitalia Diatchenko (quarterfinals)

• # 🇺🇦 Daria Snigur (semifinals, withdrew)

• # Clara Tauson (quarterfinals)