2022 Garden Open – Singles

Juan Manuel Cerúndolo was the defending champion but chose not to defend his title.

Franco Agamenone won the title after defeating Gian Marco Moroni 6–1, 6–4 in the final.

Seeds
• # 🇫🇷 Quentin Halys (semifinals)

• # 🇬🇧 Jack Draper (second round)

• # 🇮🇹 Flavio Cobolli (semifinals)

• # 🇦🇺 Christopher O'Connell (withdrew)

• # 🇷🇸 Nikola Milojević (first round)

• # 🇫🇷 Manuel Guinard (first round)

• # 🇫🇷 Hugo Grenier (second round)

• # 🇫🇷 Gilles Simon (first round)