2022 Little Rock Challenger – Singles

Jack Sock was the defending champion but chose not to defend his title.

Jason Kubler won the title after defeating Wu Tung-lin 6–0, 6–2 in the final.

Seeds
• # 🇺🇸 J. J. Wolf (first round)

• # 🇪🇨 Emilio Gómez (second round)

• # 🇺🇸 Christopher Eubanks (second round)

• # 🇦🇺 Jason Kubler (champion)

• # 🇺🇸 Michael Mmoh (first round)

• # 🇹🇷 Altuğ Çelikbilek (first round)

• # 🇦🇺 Rinky Hijikata (second round)

• # Wu Tung-lin (final)