2022 Macha Lake Open – Singles

Zheng Qinwen was the defending champion but chose to participate at the 2022 WTA German Open instead.

Sára Bejlek won the title defeating Jesika Malečková in the final, 6–4, 6–4.

Seeds
All seeds receive a bye into the second round. • # 🇭🇺 Panna Udvardy (third round)

• # 🇨🇿 Linda Nosková (quarterfinals)

• # Despina Papamichail (semifinals)

• # 🇲🇽 Renata Zarazúa (quarterfinals)

• # 🇱🇮 Kathinka von Deichmann (second round)

• # 🇦🇷 María Lourdes Carlé (third round)

• # 🇧🇷 Carolina Alves (second round)

• # 🇸🇰 Rebecca Šramková (semifinals)

• # 🇺🇸 Francesca Di Lorenzo (third round)

• # 🇨🇿 Jesika Malečková (final)

• # Conny Perrin (quarterfinals)

• # 🇨🇿 Sára Bejlek (champion)

• # 🇲🇰 Lina Gjorcheska (quarterfinals)

• # 🇪🇸 Irene Burillo Escorihuela (second round, retired)

• # 🇨🇿 Tereza Smitková (third round)

• # 🇷🇴 Andreea Prisăcariu (second round)