2022 Meerbusch Challenger – Singles

Tomás Barrios Vera was the defending champion but chose not to defend his title.

Bernabé Zapata Miralles won the title after defeating Dennis Novak 6–1, 6–2 in the final.

Seeds
• # 🇪🇸 Bernabé Zapata Miralles (champion)

• # 🇮🇹 Franco Agamenone (first round)

• # 🇩🇪 Jan-Lennard Struff (second round)

• # 🇩🇪 Yannick Hanfmann (second round)

• # 🇦🇹 Jurij Rodionov (first round)

• # 🇫🇷 Geoffrey Blancaneaux (first round)

• # 🇩🇪 Mats Moraing (quarterfinals)

• # 🇩🇪 Maximilian Marterer (first round)