2022 Open International de Tennis de Roanne – Singles

Hugo Grenier was the defending champion but lost in the first round to Otto Virtanen.

Hugo Gaston won the title after defeating Henri Laaksonen 6–7(6–8), 7–5, 6–1 in the final.

Seeds
• # 🇲🇩 Radu Albot (first round)

• # 🇫🇷 Hugo Gaston (champion)

• # Pavel Kotov (quarterfinals)

• # 🇦🇺 Jason Kubler (first round)

• # Nikoloz Basilashvili (quarterfinals)

• # 🇦🇺 Alexei Popyrin (semifinals)

• # 🇫🇷 Hugo Grenier (first round)

• # 🇪🇸 Fernando Verdasco (second round, retired)