2022 Open du Pays d'Aix – Singles

Carlos Taberner was the defending champion but chose not to defend his title.

Benjamin Bonzi won the title after defeating countryman Grégoire Barrère 6–2, 6–4 in the final.

Seeds
• # 🇫🇷 Benjamin Bonzi (champion)

• # 🇩🇪 Daniel Altmaier (second round)

• # 🇫🇷 Richard Gasquet (second round)

• # 🇫🇷 Quentin Halys (quarterfinals)

• # Pablo Cuevas (second round)

• # 🇵🇪 Juan Pablo Varillas (second round)

• # 🇪🇸 Fernando Verdasco (first round, retired)

• # 🇫🇷 Corentin Moutet (second round)