2022 Wiesbaden Tennis Open – Singles

Anna Bondár was the defending champion but chose not to participate.

Danka Kovinić won the title, defeating Nastasja Schunk in the final, 6–3, 7–6(7–0).

Seeds
• # Arantxa Rus (first round)

• # 🇸🇪 Rebecca Peterson (quarterfinals)

• # 🇭🇺 Panna Udvardy (first round)

• # 🇫🇷 Clara Burel (first round)

• # 🇫🇷 Kristina Mladenovic (first round)

• # 🇬🇧 Harriet Dart (first round)

• # Donna Vekić (first round)

• # 🇩🇪 Jule Niemeier (semifinals)