2024 Challenger Città di Lugano – Singles

Otto Virtanen was the defending champion and successfully defended his title after defeating Daniel Masur 6–7(4–7), 6–4, 7–6(7–3) in the final.

Seeds
• # 🇧🇪 Zizou Bergs (semifinals)

• # 🇫🇮 Otto Virtanen (champion)

• # 🇲🇩 Radu Albot (quarterfinals)

• # Leandro Riedi (first round)

• # 🇰🇿 Mikhail Kukushkin (quarterfinals)

• # 🇫🇷 Pierre-Hugues Herbert (quarterfinals)

• # 🇫🇷 Giovanni Mpetshi Perricard (first round)

• # 🇬🇧 Jan Choinski (second round)