2024 Guanajuato Open – Singles

Rebecca Marino won the title, defeating Jule Niemeier in the final, 6–1, 6–2.

Kamilla Rakhimova was the defending champion, but chose to compete in the qualifying competition at the Qatar Open.

Seeds
• # 🇦🇷 María Lourdes Carlé (quarterfinals)

• # 🇺🇸 Hailey Baptiste (first round)

• # 🇺🇸 Sachia Vickery (semifinals)

• # 🇩🇪 Jule Niemeier (final)

• # 🇺🇸 Ann Li (first round)

• # 🇨🇦 Rebecca Marino (champion)

• # 🇦🇷 Solana Sierra (second round)

• # 🇷🇸 Natalija Stevanović (first round)