ADX-71441

ADX-71441 is a GABAB receptor positive allosteric modulator currently being investigated as a potential treatment for anxiety, epilepsy, pain and other conditions.

Addiction
ADX-71441 has been shown to reduce alcohol consumption. This result was observed in both alcohol dependent and non-dependent animals.

There were also trials about nicotine addiction, which showed positive results: ADX-71441 was able to decrease some withdrawal symptoms of nicotine withdrawal.

Anxiety
This compound has also been shown to reduce anxiety in people with PTSD.

Pain
Experiments have shown that this compound was able to decrease hypersensitivity to pain in mice, Guinea pigs and rats.

Tolerance
ADX-71441 has been shown to have less tolerance and side effects than direct GABAB agonists, such as baclofen.