Acquired hemolytic anemia

Acquired hemolytic anemia can be divided into immune and non-immune mediated forms of hemolytic anemia.

Immune

 * Autoimmune hemolytic anemia
 * Warm antibody autoimmune hemolytic anemia
 * Idiopathic
 * Linked with primary immunodeficiency/immunodysregulation syndrome.
 * Lymphoma or chronic lymphocytic leukemia associated.
 * Secondary to other malignancies.
 * Associated with SLE or other collagen-vascular disorders.
 * Secondary to viral infection.
 * Cold antibody autoimmune hemolytic anemia
 * Paroxysmal cold hemoglobinuria
 * Drug-induced autoimmune hemolytic anemia
 * Alloimmune hemolytic anemia
 * Hemolytic disease of the newborn (HDN)
 * Rh disease (Rh D)
 * ABO hemolytic disease of the newborn
 * Anti-Kell hemolytic disease of the newborn
 * Rhesus c hemolytic disease of the newborn
 * Rhesus E hemolytic disease of the newborn
 * Other blood group incompatibility (RhC, Rhe, Kidd, Duffy, MN, P and others)
 * Alloimmune hemolytic blood transfusion reactions (i.e., from a non-compatible blood type)

Non-immune

 * Traumatic hemolytic anemia
 * Impact
 * Macrovascular defects-prostheses
 * Microvascular causes
 * Disseminated intravascular hemolysis
 * Thrombotic thrombocytopenic purpura
 * Typical and atypical hemolytic uremic syndrome
 * Other microvascular abnormalities
 * Hypersplenism
 * Hemolytic anemia due to toxic effects on the membrane
 * Spur cell anemia
 * External toxins
 * Animal or spider bites
 * Metals
 * Organic compounds
 * Infectious agents
 * Paroxysmal nocturnal hemoglobinuria (PNH)

History
The term 'acquired hemolytic anemia' originally appeared in the early 1900s.