Benidipine

Benidipine is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). It is a triple L -, T -, and N -type calcium channel blocker. It is reno- and cardioprotective.

It was patented in 1981 and approved for medical use in 1991.

Dosing
Benidipine is dosed as 2–8 mg once daily.

Mechanism
Benidipine is a calcium channel blocker.

Benidipine has additionally been found to act as an antagonist of the mineralocorticoid receptor, or as an antimineralocorticoid.

Names
Other names include Benidipinum or benidipine hydrochloride.

Benidipine is sold as Coniel by Kyowa Hakko Kogyo.

Benidipine is initially licensed for use in Japan and selected Southeast Asian countries and later in Turkey, where it is sold as 4 mg tablets.