Caymanian football clubs in North American competitions

This is a list of participation by football clubs in the Cayman Islands in North American competitions.

In 1981, Yama Sun Oil became the first Caymanian football club to participate in a CONCACAF competition, entering in the Caribbean zone of the 1981 CONCACAF Champions' Cup. They advanced to the second qualifying round before losing to SUBT of present-day Curaçao.