Clinofibrate

Clinofibrate (INN) (trade name Lipoclin) is a fibrate and a derivative of Bisphenol Z.

Synthesis

 * Clinofibrate synthesis.svg

The reaction between cyclohexanone and phenol gives Bisphenol Z (3). This is treated with chloroform and methyl ethyl ketone in the presence of base. The resulting Bargellini reaction gives clinofibrate.