D-iditol 2-dehydrogenase

In enzymology, a -iditol 2-dehydrogenase is an enzyme that catalyzes the chemical reaction


 * -iditol + NAD+ $$\rightleftharpoons$$ -sorbose + NADH + H+

Thus, the two substrates of this enzyme are -iditol and NAD+, whereas its 3 products are -sorbose, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is -iditol:NAD+ 2-oxidoreductase. This enzyme is also called -sorbitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.