Dilazep

Dilazep is a vasodilator that acts as an adenosine reuptake inhibitor.

It is used for the treatment of cardiopathy and renal disorders.

Synthesis


The reaction of bis-(3-hydroxypropyl)-ethylene diamine (1) with 1-Bromo-3-chloropropane (2) gives homopiperazine [19970-80-0] (3). Esterification by reaction with 3,4,5-Trimethoxybenzoyl Chloride [4521-61-3] (4) completed the synthesis of Dilazep (5).