Los Premios 40 Principales 2006

The first edition of the LOS40 Music Awards were held at the Palacio de Deportes de la Comunidad de Madrid on December 16, 2006. It were hosted by Frank Blanco, Sira Fernández and Tony Aguilar and marked the 40th anniversary of the radio station.

Main show

 * Dover — "Let Me out"
 * Jamelia — "Something About You"
 * David Bisbal — "¿Quién Me Iba a Decir?"
 * Moby and Amaral — Escapar
 * Lucie Silvas — "Nothing Else Matters"
 * Paulina Rubio — "Ni Una Sola Palabra"

Concerts

 * Antonio Orozco
 * Julieta Venegas
 * Maná (featuring Juan Luis Guerra)