Malonyl-CoA O-methyltransferase

Malonyl-CoA O-methyltransferase (, BioC) is an enzyme with systematic name S-adenosyl-L-methionine:malonyl-CoA O-methyltransferase. This enzyme catalyses the following chemical reaction


 * S-adenosyl-L-methionine + malonyl-CoA $$\rightleftharpoons$$ S-adenosyl-L-homocysteine + malonyl-CoA methyl ester

Malonyl-CoA O-methyltransferase is involved in an early step of biotin biosynthesis in Gram-negative bacteria.