Methylecgonone reductase

Methylecgonone reductase (, MecgoR (gene name)) is an enzyme with systematic name ecgonine methyl ester:NADP+ oxidoreductase. This enzyme catalyses the following chemical reaction


 * ecgonine methyl ester + NADP+ $$\rightleftharpoons$$ ecgonone methyl ester + NADPH + H+

The enzyme from the plant Erythroxylum coca participates in the biosynthesis of cocaine.