Mevaldate reductase

In enzymology, a mevaldate reductase is an enzyme that catalyzes the chemical reaction


 * (R)-mevalonate + NAD+ $$\rightleftharpoons$$ mevaldate + NADH + H+

Thus, the two substrates of this enzyme are (R)-mevalonate and NAD+, whereas its 3 products are mevaldate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-mevalonate:NAD+ oxidoreductase. This enzyme is also called mevalonic dehydrogenase.

In 2022, this entry was deleted from the Enzyme Classification, and is now included in with the entry for Alcohol dehydrogenase.