Milton Keynes Dons F.C. league record by opponent

Milton Keynes Dons Football Club is an English association football club based in Milton Keynes, Buckinghamshire that has competed in the English Football League (Championship, League One and League Two, the second, third and fourth tiers in English football respectively) since the team was founded. The club found itself in League One after Wimbledon F.C. relocated to Milton Keynes in 2003. The club gave back Wimbledon's trophies to the London Borough of Merton in 2007, and since then, officially, the club is considered to have been founded in 2004. The MK Dons currently compete in League Two as of the 2023–24 season.

The Dons record against each club faced in league competition is summarised below. The team's first league match was contested with Barnsley in the opening game of the 2004–05 Football League One season. They met their 93rd and most recent different league opponent, Salford City, for the first time in the 2023–24 EFL League Two season. The teams that the MK Dons have met most in league competition are Swindon Town and Walsall, against whom they have contested 26 league matches. The team has won 14 matches against Swindon, the most they have won against any team. 10 of the matches against Walsall have ended in a draw, the most draws registered by the club. Peterborough United have defeated the MK Dons 13 times each which is the most the MK Dons have lost against any team.

Key

 * The table includes results of matches played by Milton Keynes Dons in the English Football League (Championship, League One and League Two).
 * † Teams with this background and symbol in the "Club" column are competing in the 2024–25 EFL League Two alongside Milton Keynes Dons.
 * ‡ Clubs with this background and symbol in the "Club" column are defunct.
 * P = matches played; W = matches won; D = matches drawn; L = matches lost; F = Goals scored (For); A = Goals conceded (Against); Win% = percentage of total matches won
 * The columns headed "First" and "Last" contain the first and most recent seasons in which Milton Keynes Dons played league matches against each opponent

All-time league record

 * All statistics are correct up to and including the match played 27 April 2024.