N1-acetylpolyamine oxidase

N1-acetylpolyamine oxidase (, hPAO-1, mPAO, hPAO) is an enzyme with systematic name N1-acetylpolyamine:oxygen oxidoreductase (3-acetamidopropanal-forming). This enzyme catalyses the following chemical reaction


 * (1) N1-acetylspermidine + O2 + H2O $$\rightleftharpoons$$ putrescine + 3-acetamidopropanal + H2O2
 * (2) N1-acetylspermine + O2 + H2O $$\rightleftharpoons$$ spermidine + 3-acetamidopropanal + H2O2

This enzyme also catalyses the reaction:
 * N1,N12-diacetylspermine + O2 + H2O $$\rightleftharpoons$$ N1-acetylspermidine + 3-acetamamidopropanal + H2O2.