Opine dehydrogenase

In enzymology, an opine dehydrogenase is an enzyme that catalyzes the chemical reaction


 * (2S)-2- {[1-(R)-carboxyethyl]amino}pentanoate + NAD+ + H2O $$\rightleftharpoons$$ L-2-aminopentanoic acid + pyruvate + NADH + H+

The 3 substrates of this enzyme are (2S)-2- {[1-(R)-carboxyethyl]amino}pentanoate, NAD+, and H2O, whereas its 4 products are L-2-aminopentanoic acid, pyruvate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (2S)-2- {[1-(R)-carboxyethyl]amino}pentanoate:NAD+ oxidoreductase (L-aminopentanoate-forming). Other names in common use include (2S)-2- {[1-(R)-carboxyethyl]amino}pentanoate dehydrogenase (NAD+,, and L-aminopentanoate-forming).