Peptidyl-glutamate 4-carboxylase

Peptidyl-glutamate 4-carboxylase (, vitamin K-dependent carboxylase, gamma-glutamyl carboxylase) is an enzyme with systematic name peptidyl-glutamate 4-carboxylase (2-methyl-3-phytyl-1,4-naphthoquinone-epoxidizing). This enzyme catalyses the following chemical reaction


 * peptidyl-4-carboxyglutamate + 2,3-epoxyphylloquinone + H2O $$\rightleftharpoons$$ peptidyl-glutamate + CO2 + O2 + phylloquinone

The enzyme can use various vitamin-K derivatives, including menaquinone.