Talk:Β-Alanine

Moved further reading section
I moved this here, I doubt if these references were used to write the article, though they might be useful to expand it.


 * Boldyrev AA, Koldobski A, Kurella E, Maltseva V, and, Stvolinski S (1993) Natural histidine-containing dipeptide carnosine as a potent hydrophilic antioxidant with membrane stabilizing function. A biochemical aspect. Molecular and Chemical Neuropathology. 19:185-192.
 * Batrukova MA, and Rubstov AM (1997) Histidine-containing dipeptides as endogenous regulators of the activity of sarcoplasmic reticulum Ca-release channels. Biochimica et Biophysica Acta. 1324:142-150.
 * Harris RC, Marlin DJ, Dunnett M, Snow DH, Hultman E (1990) Muscle buffering capacity and dipeptide content in the Thoroughbred horse, greyhound dog and man. Comparative Biochemistry and Physiology. 97(2):249-251.
 * Harris RC, Dunnett M, Greenhaff PL (1998) Carnosine and taurine contents in individual fibres in human vastus lateralis muscle. Journal of Sports Science. 16:639-643.
 * Harris RC, Kim HJ, Harris DB, Hill CA, Kim CK, Boobis L, Sale C, and Wise JA (2005) The distribution of carnosine and taurine in different muscle fibre types from human v lateralis and the effects of beta-alanine supplementation. Amino Acids. 29:13
 * Hipkiss AR, Michaelis J, and Syrris P (1995) Non-enzymatic glycosylation of the dipeptide L-carnosine, a potential anti-protein-cross-linking agent. FEBS Lett. 371:81-85.
 * Hipkiss AR (2000) Carnosine and protein carbonyl groups: a possible relationship. Biochemistry (Mosc.) 65:771-778.
 * Hoffman JR, Ratamess NA, Kang J, Mangine G, Faigenbaum AD, and Stout JR. (2006) Effect of creatine and β-alanine supplementation on performance and endocrine responses in strength/power athletes. International Journal of Sports Nutrition and Exercise Metabolism. 16:430-446.
 * Kim HJ, Kim CK, Lee YW, Harris RC, Sale C, Harris DB, and Wise JA (2006) The effect of a supplement containing β-alanine on muscle carnosine synthesis and exercise capacity, during 12 wk combined endurance and weight training. Journal of the International Society of Sports Nutrition. 3(1): S9.
 * Stout JR, Cramer JT, Mielke M, O’Kroy J, Torok DJ, and Zoeller RF. (2006) Effects of twenty-eight days of beta-alanine and creatine monohydrate supplementation on the physical working capacity at neuromuscular fatigue threshold. Journal of Strength and Conditioning Research. Nov;20(4):928-931.
 * Stout JR, O’Kroy J, Mielke M, Zoeller R, Torok D, Cramer JT, Rakes M, and Graves BS (2006) Effects of β-alanine and creatine monohydrate supplementation on the physical working capacity at neuromuscular fatigue threshold. Journal of Strength and Conditioning Research. 20:928-931.
 * Stout JR, Cramer JT, Zoeller RF, Tork D, Costa P, Hoffman JR, Harris RC, and O’Kroy J (2007) Effects of β-alanine supplementation on the onset of neuromuscular fatigue and ventilatory threshold in women. Amino Acids 32:381-386.
 * Zoeller RF, Stout JR, O’Kroy J, Torok D, Mielke M. (2006) Effects of 28 days of β-alanine and creatine monohydrate supplementation on aerobic power, ventilatory and lactate thresholds, and time to exhaustion. Amino Acids (online, Sept. 5, 2006. 10.1007/s00726-006-0399-6).

--Dirk Beetstra T C 12:36, 20 November 2007 (UTC)

Health claims section now cites four secondary sources (reviews and meta-analyses) with similar conclusions rather than individual clinical trials.David notMD (talk) 16:00, 25 December 2016 (UTC)

Health Claims
I think that this section must be in the article and I don't quite understand why it had been removed? I've tried to cover most known effects of beta-alanine here. Healthycare (talk) 10:09, 11 January 2010 (UTC)

Topic now addressed in four references - a review, a systemic analysis, a meta-analysis and an organization position paperDavid notMD (talk) 23:52, 24 December 2016 (UTC)

Paresthesia
I know it is 'original research' but if anyone is interested: for me, the tingling sensation from ingesting B-alanine starts at about 45mg/kg. This is about 3/4 tsp or 3g for my 66kg mass. 71.139.160.208 (talk) 20:07, 16 January 2016 (UTC)

does the body use it to make carnosine or not?
these 2 statements contradict eachother: "β-Alanine is not used in the biosynthesis of any major proteins or enzymes." "β-Alanine is the rate-limiting precursor of carnosine, which is to say carnosine levels are limited by the amount of available β-alanine," Wikipaddn (talk) 20:38, 17 January 2017 (UTC)

The Ball and Stick model is incorrect
The ball and stick model shows 3 hydrogens on the nitrogen - it should be 2. I do not know how to fix it, and don't have time to learn it right now. -- 26-April-2018, William Herndon

Typos, other
Wondering if "transanimation" should be "transamination"? — Preceding unsigned comment added by 205.193.94.40 (talk) 15:20, 9 October 2018 (UTC)

It is already correct in current version of article. Amination.

--ee1518 (talk) 12:40, 30 May 2019 (UTC)

Beta-Alanine link to Aquagenic Pruritus
Date: October 31, 2018

I'm not a medical or scientific professional.

I suffer from Aquagenic Pruritus and belong to a facebook support group. Recently, one member discovered that taking Beta Alanine supplements eliminated the majority of her symptoms. Hundreds of members of the facebook group have now tried Beta Alanine and a huge number(majority) of sufferers have similar results.

Is there anyone with a medical background that can help us with further research?

Link to Facebook Group: https://www.facebook.com/groups/230640150306723/

Moylandavis (talk) 22:05, 31 October 2018 (UTC)

I don't know anything about the disease (like epidemiology = how common is it?) and I certainly don't have it myself, but here's the Wikipedia article, perhaps you can ask in talk section of that article:

https://en.wikipedia.org/wiki/Aquagenic_pruritus

--ee1518 (talk) 12:36, 30 May 2019 (UTC)