Talk:Bone marrow

Evolution
The article does not state whether bone marrow is present only in mammals or also in other classes of animals. Please amend. 74.85.71.228 (talk) —Preceding undated comment added 05:02, 6 December 2010 (UTC).

Untitled
"The tissue of bone marrow, where pluripotential hematopoietic stem cells produce blood cells, is called "myeloid tissue". Disruption of the normal myeloid tissue by cancer is the cause of two forms of leukemia." Actually, the marrow contains myeloid and lymphoid cells. All forms of leukemia (not just the myeloid forms) originate in the bone marrow. I've revised this sentence - comments? MastCell 04:33, 1 August 2006 (UTC)

how bone marrow works?
Just curious as to how the blood cells made by the marrow get into the blood stream?
 * As the cells mature, they lose various surface "adhesion" molecules that make them "stick" to the bone marrow, and they float loose into the blood. That's a vague hand-waving explanation that will probably get me laughed at, but that's the general idea. MastCell 15:51, 17 August 2006 (UTC)

Also, the image of the leukemic (blast) cells is not a bone marrow. It is a peripheral blood smear. 167.94.2.9 (talk) 07:44, 1 February 2008 (UTC) EAY, MT (ASCP)

Purpose of bone marrow?
Could someone clarify the purpose of bone marrow? Why did we evolve bone marrow? I can somehow deduce this from the "type of cells" but its somewhat vague and I would expect this explanation in the summary. Rngadam (talk) 08:26, 26 October 2008 (UTC)

The bones protect developing stem cells from UV light. As fishes evolved into frogs and began to walk on land, the stem cells moved from the kidneys, which could no longer provide adequate protection from UV, into the bones of the legs. Someone should add a paragraph to the article to explain this. Wmjohn6217 (talk) 14:29, 29 July 2019 (UTC)

Difference between red and yellow marrow?
The intro says that bone marrow is the place where blood cells originate, but is that true for yellow marrow? The difference between yellow and red marrow should be explained in the article. AxelBoldt 22:19, 15 October 2006 (UTC)


 * Yellow marrow is just marrow with fat in it. - Nunh-huh 01:06, 16 October 2006 (UTC)


 * For what little I've read, there's a definite difference between red and yellow that needs explication. As I understand, we start developmentally with red marrow and, as we age, develop yellow marrow.  Yellow marrow also either doesn't produce blood cells at all or produces only a few kinds. Satarnion 03:33, 17 October 2006 (UTC)

Actually we are born with both yellow and red marrow, but it isn't true that the yellow marrow is just all fat becuz white blood cells can actually develop in yellow marrow but not all the time and BOTH yellow and red marrow have fat cells on it.. =] Pretty Ricky aint breakin up yall! yay!! Tam` Tam` =] 04:23, 3 April 2007 (UTC)

Red marrow and yellow marrow are descriptive terms for the appearance of the bone marrow to the naked eye. In humans, the red marrow occupies the central (axial) skeleton (skull, vertebrae, ribs, pelvis) and the most proximal parts of the humerus and femur. The remainder of the skeleton is yellow marrow. At a light microscopic level, red marrow contains both haemopoietic (blood cell precursor) cells and fat cells. Yellow marrow is almost all fat cells. In some disease states (anaemia, leukaemia), marrow sites that were yellow can turn red as haemopoiesis starts taking place there.(Jon salisbury 11:15, 28 June 2007 (UTC))
 * Agree, and the phrasing of this article is misleading. In fact, much of this article seems to be written by someone with fairly superficial grasp on the topic. I will work to expound on this red/yellow distinction in the future. Dr G (talk) 20:41, 27 December 2017 (UTC)

I can't figure out why someone erased "unknown" a couple edits ago...

Marrow as metaphor
Bones and skeletons in iconography and world symbolism may be understood as metaphorical of the unseen or myserious structure and design that holds, orders and contains the patterns of being extant and extinct in the Universe. By metaphorical extension, marrow is the quintessential at the core of the hidden structure: Mystery.

Article Bias
This article is not only poorly written (alas most of Wikipedia is), but is also biased toward humans. Is it not true that most non invertebrate life has this sort of tissue? Perhaps an issue of unbiasing this article could be acomplisherd? Ask D.N.A.- Peter Napkin (talk) 04:40, 16 March 2008 (UTC)


 * I agree with this assessment, but I don't know enough about marrow to revise effectively. Marrow is clearly present in all mammalia; not in fish (though they may have a cold-blooded equivalent); I don't know about birds (I think they're hollow-boned, though, which would seem to preclude marrow?)  anyone with any real knowledge of this out there?  -- Ludwigs 2  04:14, 17 February 2009 (UTC)

Poorly written
Under "diseases": "What is it I bet you're asking, well..."

That's unacceptable. 71.11.215.216 (talk) 04:23, 21 May 2008 (UTC)

Requesting expansion.
Bone marrow's culinary use really deserves its own article, not a two sentence quip as a subheading. Anyone with sufficient knowledge to write it should go for it, IMO, as it's becoming increasingly popular in the US as Americans slowly realize that it is okay to eat things that aren't chemical-filled, prepackaged crap. —Preceding unsigned comment added by 70.20.18.122 (talk) 22:34, 15 August 2008 (UTC)


 * should we expand the article brain to include the culinary tastes of Zombies, too?   -- Ludwigs 2  04:31, 17 February 2009 (UTC)

donating bone marrow
Is there an age limit for donating bone marrow ? —Preceding unsigned comment added by 86.151.89.1 (talk) 19:15, 5 February 2009 (UTC)

Advertising
I know bone marrow donation is encouraged, but the External Links to marrow donation centers don't seem appropriate. They're not providing more information on bone marrow, they're advertising. Unless I get any strenuous objections, I'm removing all marrow donation links for violation of WP:ADS. --ShadowRangerRIT (talk) 21:21, 28 October 2009 (UTC)
 * Rather than wait, I decided to remove it immediately. Every entry was either advertising for marrow donors or, in two odd cases, recipes for food made with marrow. None of it was appropriate for this article. --ShadowRangerRIT (talk) 21:26, 28 October 2009 (UTC)
 * I completely agree with your removal of the links. However, we should do some digging around and see if there's a "national" site for bone marrow disease & donation (like cancer's "national" site is the National Cancer Institute, etc.).

There are several national sites. I've heard about this issue because my nephew's son has a disease that will need a bone marrow donation. you can find several links to various national sites for more information at www.hope4noah.org (the site that my nephew and his wife have established recently). The links were helpful. I wonder if a collection of links could be added or at least a mention in the article cold be made to note that there is an ideal time for bone marrow donation... between 18 and 60 according to one site that is linked to http://www.hope4noah.org.

\\about the assertion that the donation sites "aren't providing more information on bone marrow," perhaps you have not had an opportunity to look at some of the sites. The graphic images are quite helpful in understanding the process. in particular you can see www.dkmsamericas.org/sites/default/files/iframes/bonemarrowdonation to see a helpful graphic and explanation of the process of bone marrow donation. The wikipedia article does not make it clear that donation can change lives. perhaps at least some graphic images can be

the prohibition on advertising is certainly admirable. Psychological investigation of what it takes to inform many people indicates that a measure of persuasion is often needed, above the information-sharing that takes place on most wikipedia sites. perhaps the justification for including some of the bone marrow sites would be to show examples of the high level of generosity and good will that takes place. theebookman Theebookman (talk) 10:04, 25 November 2012 (UTC) TheEbookman

anyone eat bone marrow?
I bite open chicken bones and eat the bone marrow —Preceding unsigned comment added by 86.5.96.31 (talk) 17:56, 22 February 2010 (UTC)

Of course people eat it. I just made stew with Beef Marrow in it not two days ago. I don't feel comfortable (nor do I have the time) to do an update myself now, but, here is a thread that I found with a load of references that could be used in an updated section or two http://answers.google.com/answers/threadview/id/112897.html and also.... http://www.wellsphere.com/healthy-eating-article/bone-marrow-delicious-nutritious-and-underappreciated/1068421 —Preceding unsigned comment added by 98.110.171.81 (talk) 18:23, 14 December 2010 (UTC)

Bone marrow as food
Bone marrow as food has been completely removed from the aricle. If it is supposed to be a purely medical article, there should be a second article about that kind of food.

In Germany for example, bone marrow balls for soup are a very common thing, you can buy it in most supermarkets.

Look at the German articles about bone marrow as food:


 * 1) Mark (Lebensmittel) – "marrow (food)"
 * 2) Markklößchen – "bone marrow balls"

Translation of the introduction of the first German article:
 * "Mark (marrow) is the soft content found inside of hollow bones. In cuisine the yellow bone marrow of long bones ("Knochenmark" – bone marrow) is used as well as the spinal cord ("Rückenmark" – spinal marrow) – especially from cows and calves."

Translation of the introduction of the second German article:
 * "Markklößchen ("bone marrow balls") (in Austria also Markknödel) are little balls/dumplings of white bread and bjsasKLone marrow or spinal cord/marrow from cow or calf, which are served in soups.

--Erlenmayr (talk) 12:03, 28 January 2011 (UTC)

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Bone marrow
I don’t understand by bone marrow by there is no bone in the process 150.107.232.25 (talk) 09:05, 28 February 2023 (UTC)