Talk:C57BL/6

"(beware, it may bite)."
I don't think this little statement is necessary. It also sounds unprofessional. I'm taking it out for now. BigSciZot 19:14, 11 October 2006 (UTC)

Should become part of a "laboritory mouse strains" article
but it's such a common one it does possible deserve it's own page, it would be really usefull tro have articles on each of the popular lab strains


 * FYI, there is now a Laboratory rat page, though that doesn't necessarily mean that the mouse pages have to be consistent with this format. --Jcbutler (talk) 03:29, 16 September 2008 (UTC)

Should remain independent article
B6 is one of the most commonly used inbred strains, used all over the world. The article could easily be expanded (but I don't have the time for that). Crusio


 * Very common lab strain, I spent 6 weeks tending these little bastards and I developed a fondness for this strain in particular. Very much cuter than C5 mice and less skittish.  Little whitish tufts of fur behind the ears and at tip of the tail, very jumpy at 2 weeks and pretty decent climbing ability.  Raised in a lab/breeding facility they are rather docile and not difficult to catch should one get loose.  24.126.102.48 (talk) 04:12, 24 April 2008 (UTC)

C57BL/6 as a "Th1 responder" and Response to diseases
I feel that these sections are not at the right place here. Why highlight the Th1 and Plasmodium sensitivity characters out of the hundreds and hundreds that have been studied in these mice? If this material is important, it should be moved to other articles, but I think it should be deleted here. --Crusio (talk) 17:02, 11 May 2008 (UTC)

Jackson Lab
This strain was created in Jackson Lab and it is the largest supplier. Please update it! (I cant because I work there). —Preceding unsigned comment added by 209.222.197.86 (talk) 18:51, 30 July 2008 (UTC)


 * C57BL/6 was created by Clarence Little, the first director and founder of JAX. However, he created the strain in 1921 (see here on the JAX site), whereas the Jackson Labs didn't come into being until 1929. In addition, JAX may be the largest supplier of C57BL/6J, but it probably is not the largest supplier of some other substrains, such as C57BL/6N. --Crusio (talk) 19:18, 30 July 2008 (UTC)

They are the most widely used lab mouse strain, due to the availability of congenic strains, easy breeding, robustness, and their relationship to GM models, making them ideal controls.
"and their relationship to GM models, making them ideal controls." This statement is unnecessary in my opinion. Of course this strain will be a good control for animals that have a mutation in the same background. Strain X is an ideal control for Genetically Modified Strain X mice. This statement could describe any lab strain and is not specific to C57BL/6, so I removed it. Does anyone disagree? —Preceding unsigned comment added by JjusticeIV (talk • contribs) 18:46, 15 July 2010 (UTC)

Tendency to bite?
from the article: "...an easily irritable temperament. They have a tendency to bite and cannot be handled like a typical pet mouse or more docile laboratory strains such as BALB/c"

This seems to just be someone's point of view, without any support. My own POV is that I've been working with B6 mice for over 5 years, and have only been bitten VERY rarely (and always under abnormal situations, such as when attempting to perform some invasive procedure). Under routine handling I've never been bitten - and I normally just allow the mice to rest on my hand, so they have had plenty of opportunity to bite if they felt like it. — Preceding unsigned comment added by 142.244.112.172 (talk) 23:07, 23 March 2012 (UTC)


 * This appears to be a very common point of view. Do you have experience with other kinds of mice?  I understand that pet mice almost never bite.  WhatamIdoing (talk) 06:36, 20 June 2013 (UTC)
 * I have worked with B6 animals for decades, and not just with them. They're not extremely "bity" (especially compared to wild mice), but much more than most strains. Pet mice or BALBs rarely bite. In my experience this statement is true. --Randykitty (talk) 09:49, 20 June 2013 (UTC)

Subjective statements
Someone from a major research center that uses these mice is removing a colorful, memorable description of the limitations of this particular strain because it is "subjective". I believe that it's "brilliant writing", which is a desirable thing on Wikipedia.

Wikipedia does not have a "no subjective statements" rule or a "scientists only" rule. Instead, we try to fairly, proportionately, and, as far as possible, without bias, describe all of the significant views that have been published by reliable sources on a topic. This includes the views published by mere science journalists. WhatamIdoing (talk) 06:47, 20 June 2013 (UTC)
 * I wouldn't necessarily call this "brilliant" writing, but it's sourced and not incorrect either. It should stay. --Randykitty (talk) 09:51, 20 June 2013 (UTC)

Pain study
Remark about most pain studies use male mice seems unrelated to this article. It is not specific to this strain of mice.137.82.157.77 (talk) 04:11, 24 January 2015 (UTC)

"due largely to inertia"
This is a strange (and in my opinion incorrect) use of the word inertia. I suggest replacing it with "feedback loop". 121.134.187.240 (talk) 15:30, 10 October 2015 (UTC)

Behavior
I thought it odd that the phrase "barbering behavior" is used -- particularly since the word "barbering" is linked to an article on the human behavior. Shouldn't this be more properly referred to as "grooming behavior" -- or is there perhaps a more technical term that is more accurate to such animal behavior? Jdevola (talk) 18:03, 17 February 2020 (UTC)