Talk:Creatine

Wiki Education assignment: Science Communication
— Assignment last updated by Prad8960 (talk) 02:20, 1 February 2023 (UTC)

Is creatine as same as steroids?
Is creatine as same as steroids? 60.243.208.198 (talk) 05:25, 13 February 2023 (UTC)


 * No, creatine is not a steroid. 109.48.2.151 (talk) 16:45, 25 April 2023 (UTC)

Proportion of the 3 aminoacids?
I can't find any article online that specify the proportion between the 3 amino acids. If methionine is "an additional requirement", it implies that its proportion in the creatine is low. If someone can find something, put a link on this paragraph in the article.

"Creatine is not an essential nutrient. It is an amino acid derivative, naturally produced in the human body from the amino acids glycine and arginine, with an additional requirement for S-Adenosyl methionine (a derivative of methionine) to catalyze the transformation of guanidinoacetate to creatine." 37.181.51.115 (talk) 21:53, 19 July 2023 (UTC)
 * It takes one of each of them. The portions that come from glycine and arginine are color-coded in the image just below the paragraph you were reading. And SAM is just a carrier of the methyl group (see the "SAM cycle" section of the article for that amino acid for more information). DMacks (talk) 22:05, 19 July 2023 (UTC)

Kidney Function/Safety
The first sentence under the Renal Function section says "Long-term creatine supplementation has not been proven safe for kidney patients." The provided reference for this paraphrased comment is an article from Current Sports Medicine Reports written in 2002.

Subsequently, we've had decades of research. For example, the next paragraph which discusses a systematic review and meta-analysis in 2019 published by the National Kidney Foundation, Inc., which found that "creatine supplementation does not induce renal damage in the studied amounts and durations".

Relative to this and an abundance of more recent articles & research, the 2002 reference is very dated, a relatively weak reference to begin with (not a scientific study; not a direct quote), and consequently seems undue as the first sentence in the section.

Can we let the latest research speak for itself, or perhaps find a much more recent, highly credible/reliable source and provide a more direct quotation on the topic of safety for people with preexisting kidney problems? -- Kalem014 (talk) 14:27, 20 May 2024 (UTC)