Talk:D-dimer

Pregnancy info
ml as normal also apply for pregnancy? Some reference states that pregnancy can increase coagullation factors such as d-dimer and fibrin. borgx ( talk ) 01:08, 26 May 2006 (UTC)


 * In pregnancy, D-dimer is likely to be elevated and loses its use a diagnostic tool. No different normal range is used, because by increasing the cutoff you'd lose its sensitivity. In pregnancy clinical assessment and V/Q scanning is used. JFW | T@lk  19:06, 26 November 2006 (UTC)

ui7uhyyjg — Preceding unsigned comment added by 124.124.76.138 (talk) 06:27, 24 August 2017 (UTC)

Specificity
D-Dimer is not specific to DVT therefore all clinical details should be considered before making a diagnosis


 * It is not specific for anything. JFW | T@lk  19:06, 26 November 2006 (UTC)

Specificity (as in "sensitivity and specificity" of a test) has nothing to do with whether the test is specific to one disease as opposed to other diseases. Specificity means to which degree the test gives negative test result for persons for whom we know in advance that they do not have the disease in question (and do not have any of the alternative diseases either that the test might be sensitive to). Gbwi (talk) 14:12, 23 September 2013 (UTC)

UFB
The way forward: perhaps it's urinary fibrinopeptide B - see. One of my seniors was waxing lyrical about its diagnostic utility. JFW | T@lk  01:18, 21 December 2006 (UTC)

Pregnancy
Normal D-dimer in pregnancy still excludes DVT JFW | T@lk  06:36, 7 August 2007 (UTC)

D-dimer >3000
Finally, there is some correlation between a "whopping D-dimer" and mortality - as everyone had sneakily suspected JFW |  T@lk  21:24, 22 November 2007 (UTC)

Genetic variation
In European Americans, 2% of the variation in D-dimer levels is due to polymorphisms in various fibrinolysis-related genes such as fibrinogen, PAI-1 and plasminogen. In African Americans the sample was too small to establish any linkage. Fibrinogen mutations, in particular, explained D-dimer levels >20% higher than controls. JFW | T@lk  10:53, 18 January 2008 (UTC)

Review
could serve as a good review on the D-dimer antigen and its diagnostic relevance. JFW | T@lk  17:03, 26 March 2009 (UTC)


 * - meta-analysis of use of bedside test in outpatients. JFW | T@lk  23:50, 24 November 2009 (UTC)


 * http://atvb.ahajournals.org/cgi/content/abstract/29/3/332 may be helpful. JFW | T@lk  00:07, 25 November 2009 (UTC)


 * Another review with a historical angle JFW |  T@lk  00:15, 25 November 2009 (UTC)

Young and health
added the following:


 * ,particularly in young and healthy patients <!ref name=Qaseem>

None of my other sources mention this age issue. I will need to read the source carefully and see if this could be mentioned. JFW | T@lk  20:52, 17 January 2010 (UTC)

What is a normal d-dimer range and units?
A normal d-dimer range is between 0 and 200 in patients with VTE this level may reach 3000 — Preceding unsigned comment added by 92.22.2.188 (talk) 17:05, 4 July 2016 (UTC)

I heard 500. Jennifer H. Jones (talk) 10:53, 23 May 2010 (UTC)


 * Depends on the analyser used. JFW | T@lk  07:28, 6 June 2010 (UTC)


 * See DVT for more explanation. Biosthmors (talk) 16:56, 11 December 2012 (UTC)

Use easy english
It should be obviously said- D dimer is used to rule out clots. It needs to be more succinct I think 182.255.99.214 (talk) 11:59, 24 November 2015 (UTC)

Detailed review
10.1080/10408363.2018.1529734 JFW &#124; T@lk  15:47, 29 April 2020 (UTC)

For ruling out clotting from Covid vaccines
In the covid vaccine resistance movement, there is much talk of microscopic blood clots. Some opponents of the vaccine, for instance from the Orange County Board of County Commissioners, suggested that every vaccinated person should get the D-dimer test to know if they have gotten clotting from the vaccine. While this is probably not the place to address the advisability of this, it should be mentioned since it is in the public discourse. — Preceding unsigned comment added by Contraverse (talk • contribs) 20:20, 22 December 2022 (UTC) Contraverse (talk) 15:42, 6 January 2023 (UTC)