Talk:Endothelin

Comment on rating
The article is rudimentary but the topic -- the endothelin family of peptides -- is among the most important in physiology, as these peptides are involved in vascular, neuronal and other functions. Few peptide groups have such diverse regulatory actions. The above banner on the Talk page, This article is on a subject of Low-importance within molecular and cellular biology, is inappropriate and inconsistent with fact. --Paul144 (talk) 23:09, 18 March 2008 (UTC)

Urotensin
Urotensin is only more potent than ET in certain species and has a lesser maximal response. Thus it is inapproprate to say that ET has been "dethroned".

that's absolutely true, urotensin is not more potent than endothelin. For instance, urotensin-II does not induce any vasomotion of pial arteries in the rat.