Talk:Helix-turn-helix

bHLH
A certain receptor, AhR (aryl hydrocarbon receptor) and other transcription factors have, according to my sources, "a basic helix-loop-helix motif". I'd like to know if basic in this context means "elementary, simple, merely functional" or alkaline, the opposite of acidic. -Samulili 20:01, 9 May 2006 (UTC)
 * the latter - it's a frequent feature of DNA binding motif nomenclature, for example in the bZIP domain of the Leucine zipper DNA binding motif, the DNA binding region comprises a number of basic aminoacids such as arginine and lysine. Philbradley 14:21, 9 December 2006 (UTC)

Merger proposal
I think Winged helix turn helix should be merged with this page, to go in a separate section. This is one of many variants of the helix turn helix domain which is likely to have arisen from a single ancestor (see PMID:15808743) and this article should be expanded to encompass these. --RE73 (talk) 11:47, 25 October 2011 (UTC)


 * Agree Alexbateman (talk) 13:44, 25 October 2011 (UTC)

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