Talk:P2X purinoreceptor

Suggestions for additions and improvements
Subcellular (talk) 16:20, 7 April 2008 (UTC)  Gene info boxes interfere with page format (all the edit tabs are displaced).
 * Given there are now pages for each receptor subunit, the gene infoboxes area little redundent here aren't they? This page should not contain such specific information, which should only be on the specific gene pages.  For example like nAChRs WW9066 (talk) 21:36, 18 April 2008 (UTC)
 * OK, I agree that including 7 protein boxes in one article was a little excessive. I have removed the protein boxes, but have converted the receptor subtype list into a table so that at least the chromosomal location of each of the receptors gene is retained.  I hope that this is an improvement.  Boghog2 (talk) 14:30, 19 April 2008 (UTC)
 * Thanks for that, I like the new table. I would have made the changes myself (I'm slowly getting the hang of editing pages myself) - though I probably wouldn't have such a good job. WW9066 (talk) 19:44, 19 April 2008 (UTC)

I appreciate that this should probably be on the specific pages (though they are very quiet currently, and this is a kind've parent page to all seven), but should those pages be named after the gene name or the protein name? I think at least I shall put some redirects in. Is there a wikipedia convention for this in Biological articles? Presumably the article should cover both the gene and protein, as it would be total over-kill to have separate articles for the gene and protein.WW9066 (talk) 19:44, 19 April 2008 (UTC)


 * With very few exceptions, each gene and the corresponding protein encoded by that gene has one and only one WP article whose subject matter comprises both the gene and the protein. The reason I included both the P2X receptor and corresponding HUGO gene name in the table was primarily to inform the reader that the names of the gene and protein differ slightly.  Cheers.  Boghog2 (talk) 22:52, 19 April 2008 (UTC)

Discussion regarding changes
I've updated the page to take into account the recent publication of the P2X4 crystal structure, and added a couple of figures.

BTW, the IP address 165.134.61.45 in the History is all me (neglected to log in). Subcellular 18:02, 6 August 2009 (UTC)
 * Nice work Subcellular. The figures look great!  Boghog2 (talk) 18:33, 6 August 2009 (UTC)
 * thanks. and thanks for posting the info box, i neglected to do that. At the moment, the pdb file only features a single subunit. when there's a full structure file, I'll tinker with it in Pymol and put up a better pic.Subcellular 20:48, 6 August 2009 (UTC) —Preceding unsigned comment added by Subcellular (talk • contribs)

P2XLR1?
Isn't this more commonly known as P2X6? I know it doesn't form homomeric receptors, but within the field it's more commonly known as P2X6. What is the consensus?WW9066 (talk) 21:24, 18 April 2008 (UTC)
 * Apparently the official HUGO gene name was until recently P2XLR1 but has now changed to P2X6. Therefore I have made the corresponding changes in the text of this article.  Cheers.  Boghog2 (talk) 21:52, 18 April 2008 (UTC)

Reorganization!
Greetings! I have reorganized the page so that it flows from more general to more specific. In additon, I have expanded the information on this page to include more detailed information about the structure, channel opening, receptor synthesis, and receptor trafficking. I also added multiple citations to substantiate claims already present on the page, besides adding some of my own. Bcaruso54 (talk) 22:54, 29 April 2013 (UTC)