Talk:Peroxisome proliferator-activated receptor

human ppar-delta activation
where can i get ppar-delta activating medicaments? —The preceding unsigned comment was added by 84.61.15.154 (talk) 12:50, 31 March 2007 (UTC).


 * What would you like to achieve with that? JFW | T@lk  21:23, 27 November 2007 (UTC)

Muraglitazar
We should perhaps quote Steven Nissen's destruction of muraglitazar as an antidiabetic. Obviously, we still know too little about PPAR to predict firmly what modulation will do to bone and coronary artery. JFW | T@lk  21:23, 27 November 2007 (UTC)


 * RE: Muraglitazar: I presume you mean this?  Boghog2 (talk) 21:47, 27 November 2007 (UTC)


 * RE: PPAR modulators effect on bone: this looks sobering: Boghog2 (talk) 21:47, 27 November 2007 (UTC)

PPAR/plant sterols/and natural alternatives?
I have a couple of questions I hope someone here can help me answer. First, seeing as plant sterols can also reduce cholesterol and I beleive, increase the HDL, does it have any impact on PPAR's? Also, are there any known natural or herbal alternatives that also activate PPAR? —Preceding unsigned comment added by Interestedperson (talk • contribs) 05:07, 4 January 2009 (UTC)

Banned?
This was dropped on the article:

PPARs drugs are banned as a doping substance under the World Anti-Doping Agency Code since 2009. WADA issued a warning in Mar 2013 although details prompting the sudden announcement is unknown: https://theconversation.edu.au/anti-doping-agency-warns-cheats-on-the-health-risks-of-endurobol-12997

This sounds almost like rumour, and a bit more logical explanation would be useful. What might the beneficial effects be of PPAR ligand use? JFW &#124; T@lk  22:35, 24 March 2013 (UTC)


 * The effect is mediated specifically by PPARδ and activation of PPARδ increases running endurance (see for example ). Boghog (talk) 22:49, 24 March 2013 (UTC)

Assessment comment
Substituted at 02:39, 30 April 2016 (UTC)