Talk:SN1 reaction

Untitled
I don't think that "step 3" (deprotonation step) is necessary for SN1. This implies that all SN1 should have a deprotonation step, which is not true. Absurdpoet 18:38, 7 July 2015 (UTC)

"Nuclophiclic attack": is that "nucleophilic attack"? The Anome 22:00 7 Jun 2003 (UTC)


 * Yep, typo. --Menchi 23:01 7 Jun 2003 (UTC)

Should SN1 and SN2 have some kind of link to each other? Or could they be combined? --Gregoe86 06:37, 27 November 2005 (UTC)


 * Thanks for pointing that out. I did a big rewrite of all these pages recently, but I failed to link them together properly.  I have added a mention of SN2 in the intro, and all of the nucleophilic substitution pages now have "See also" links.  As you can NOW see, there are not only separate SN1 and SN2 articles which contain a lot of specific details, we also have a combined nucleophilic substitution article which gives a broader picture.  The latter article includes a comparison of SN1 vs SN2, and also it is intended to cover aromatic, acyl and non-carbon substitutions in a similar way once I or someone else finds time to write that. Thanks, Walkerma 05:35, 28 November 2005 (UTC)


 * You're welcome! I have an exam on all this stuff tomorrow, and have been using wiki for some different explanations than my textbook.  Well written articles, all in all. Gregoe86 18:28, 28 November 2005 (UTC)

Diagrams
Just for the sake of completeness, I’ve started adding in mechanistic diagrams of nucleophilic substitution and elimination reactions that include electron movement. I’m attempting to do these diagrams to enhance the existing example mechanisms already written by Walkerma. Please let me know if I’ve missed something in them. Thanks. --AirMonk 20.23 9 Dec 2005 (UTC)


 * Thanks! There's a lot still to be done on this article, I appreciate your work, especially as some of my students may be reading this page ready for their exam next week!  Don't hide your diagram as a thumbnail, though.  Cheers, Walkerma 20:28, 9 December 2005 (UTC)

-Diagram-

Is it just me or is the diagram incorrect, the overall reaction quotes the Tert-Butyl-Bromide correctly but in the first step is written incorrectly?
 * You're right, it looks like someone put isopropyl bromide (2-bromopropane) in there by mistake. I'll see if I can paste the right structure in.  Walkerma 20:22, 4 February 2007 (UTC)
 * OK, if you reload the page it should look right now. Thanks for pointing that out! Walkerma 20:32, 4 February 2007 (UTC)

meaning of SN1
SN1 stands for substitution -nucleophilic-first order [not unimolecular,an older term] similarly,SN2 is substitution-nucleophilic-second order[not bimolecular] E1 and E2 are defined similarly in terms of order and not molecularity —Preceding unsigned comment added by 59.88.36.151 (talk) 18:17, 7 October 2008 (UTC)


 * I don't think so. Recent books still call it unimolecular, and in fact molecularity is not the same as reaction order. See . --Itub (talk) 20:31, 10 October 2008 (UTC)


 * Reread the article. It states First Order reaction kinetics, not reaction order: the rate of reaction depends on a single reactant concentration. SN2, the rate of reaction depends on both reactant concentrations. Three body reactions are rare and low probability of all three tree reactants coming together. (Before you mention Hydrogenation, reactions that require a substrate to occur include the substrate "concentration" as part of the constant in the equation of reaction.) See my note below re "textbook" SN1 reactions are actually non-existent. Shjacks45 (talk) 19:00, 21 September 2013 (UTC)

No mentioning about Arenes
In case of arenes, SN1 reaction is ruled out as the the phenyl cation is too unstable to carry SN1 reaction. (Hence haloarenes prefer SN2 reactions). However it is not mentioned in the topic here. It is very important. Exceptions should be mentioned. Valchemishnu Valchemishnu 12:58, 26 May 2011 (UTC) — Preceding unsigned comment added by Valchemishnu (talk • contribs)

Textbook SN1 reactions are actually incorrect
My Chemistry Professor at UCSB was disturbed by a textbook illustration "proving" SN1 hydrolysis of halide as a straight line graphed through a series of non-linear points (statistically inconclusive confidence level in the data). ("Thiry caliber pencil" in military terms; common for scientists to fudge research results to get published.) She had several students redo the results with newer lab equipment and published. However the SN1 rubbish is still peddled in undergrad textbooks. This implies that e.g. 2-BromoButane will racemize in a non-reactive polar solvent say NaBr in DMSO ith first order kinetics also but that is not the case. Kinetics are actually somewhere between SN1+ and SN2-. Admittedly this an easy simplification for high school or freshman Chemistry. Shjacks45 (talk) 19:35, 21 September 2013 (UTC)

Yeah because DMSO favors SN2 in that situation, of course you're going to get both situations. Secondary SN1 is a bit controversial, but this isn't data. — Preceding unsigned comment added by 168.156.42.7 (talk) 15:59, 20 July 2016 (UTC)

Assessment comment
Substituted at 05:11, 30 April 2016 (UTC)

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