Talk:Tunneling nanotube

Untitled
The Gerdes Group link is broken. TristramBrelstaff (talk) 11:45, 20 November 2008 (UTC)
 * Fixed, thank you. Tim Vickers (talk) 17:27, 20 November 2008 (UTC)

Technically they were first observed as early as 2000 (by Rustom), it's just that Gerdes and Rustom didn't publish their landmark paper until 2004. 86.1.163.237 (talk) 12:32, 21 November 2008 (UTC)


 * Was that first publication Biotechniques. 2000 Apr;28(4):722-8, 730 ? I've looked through that paper but can't find any mention of intercellular membrane structures, it seems to deal exclusively with intracellular vesicle trafficking. Is there another paper or am I missing something? Tim Vickers (talk) 16:22, 21 November 2008 (UTC)


 * From "Tunnelling nanotubes: Life's secret network". New Scientist November 2008, (last external link that I just added in article "Membrane nanotube") opening paragraphs...


 * " HAD Amin Rustom not messed up, he would not have stumbled upon one of the biggest discoveries in biology of recent times. It all began in 2000, when he saw something strange under his microscope. A very long, thin tube had formed between two of the rat cells that he was studying. It looked like nothing he had ever seen before.
 * His supervisor, Hans-Hermann Gerdes, asked him to repeat the experiment. Rustom did, and saw nothing unusual. When Gerdes grilled him, Rustom admitted that the first time around he had not followed the standard protocol of swapping the liquid in which the cells were growing between observations. Gerdes made him redo the experiment, mistakes and all, and there they were again: long, delicate connections between cells. This was something new - a previously unknown way in which animal cells can communicate with each other.
 * Gerdes and Rustom, then at Heidelberg University in Germany, called the connections tunnelling nanotubes. Aware that they might be onto something significant, the duo slogged away to produce convincing evidence and eventually published a landmark paper in 2004 (Science, vol 303, p 1007)." Darrell_Greenwood (talk) 18:35, 21 November 2008 (UTC)

OK, I've corrected the article to say "first described in 2004". Please feel free to expand the article yourself by the way, I'm far more comfortable with biochemistry myself than cell biology! Tim Vickers (talk) 20:19, 21 November 2008 (UTC)

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