Vitamin D3 24-hydroxylase

Vitamin D3 24-hydroxylase (, CYP24A1) is an enzyme with systematic name calcitriol,NADPH:oxygen oxidoreductase (24-hydroxylating). This enzyme catalyses the following chemical reaction


 * (1) calcitriol + NADPH + H+ + O2 $$\rightleftharpoons$$ calcitetrol + NADP+ + H2O
 * (2) calcidiol + NADPH + H+ + O2 $$\rightleftharpoons$$ secalciferol + NADP+ + H2O

Vitamin D3 24-hydroxylase is a heme-thiolate enzyme (P-450).